Movement is very important in Guild Wars.  The WASD and the arrow keys will
move your character in the respective direction when pressed.  Q and E will
strafe you left or right.  Strafing is a great way to dodge most incoming
missile projectiles.  If you have no reason to be standing still during battle,
always be strafing in a random pattern.  Different projectiles do have
different movement rates and arcs, I will leave it to you to get a feel for
these.  Practice strafing early on enemies which do lousy damage, so when you
reach those who hit hard, you are not always getting hit.

The space bar doubles as the left click button of a mouse.  It will attack
whatever target is active, or talk to whatever NPCs is selected.  Tab, [, and ]
will scroll through targets.  C will target the closest enemy, f will target
yourself, and v any nearby NPCs.  T will target a called target, more on this
in a moment.

Calling targets is an integral part of Guild Wars.  It allows one party member
to display which enemy he or she is attacking to the entire party.  Generally,
a healer is called first so that it can be taken out quickly.  To call a
target, hold control whenever you hit it with an action [control double click
would say “I’m attacking blah blah blah”.  When a party member hits T, they
will also target blah blah blah.  It is best to only have one assigned caller
in a party.  Multiple people calling is usually confusing and annoying.

You can also use control to “say” just about anything.  Control + clicking on
virtually anything on your display interface will result in some sort of
statement.  You can inform healers what conditions you have on yourself, to
state you have low energy, or low health.

In Guild Wars, all characters start at level 1 with 100 health.  Like many
RPGs, Guild Wars is to some extent based on level.  Each time you level your
maximum health increases by 20.  In addition, you get attribute points, which
are used to improve the quality of your skills by boosting the corresponding
attribute.